Dosimetric evaluation of physical parameters for different energies in advance radiotherapy technique for Liver cancer

Document Type : Original Article

Authors

1 National Cancer Institute (NCI), Cairo University, Cairo, Egypt

2 Physics department, faculty of sciences, Beni-Suef University, Egypt

3 Medical Radiation Physics - Al Azhar University

4 Nuclear and Radiation Physics Research Laboratory, Physics Department, Faculty of Science, Beni-Suef University,

Abstract

ABSTRACT
Introduction: This work aimed to study dosimetrically compare 6MV, 10MV and dual energies (DE) photon beam energies in liver cancer, evaluating the effect of using different of energies on intensity-modulated radiation (IMR) outcome were selected.IMRT treatment plans Identical optimization constraints were applied for all energy plans. The parameters like beam angle, number of beams, were kept constant to achieve the same clinical objectives. Both qualitative and quantitative methods were used. many physical indices for Planning Target Volume (PTV), the relevant Organs at Risk (OARs) as mean dose (Dmean), maximum dose (Dmax), 95% dose (D95), integral dose, total number of segments, and also the number of monitor unit (MU) were applied.
Materials and methods: 28 virtual IMRT treatment planning were involved in this study. Step-and-shoot IMRT treatment plans were designed. Plans depended on Monaco (IMRT) treatment plan outcome. For each case, three plans with the same beam geometry were created using 6 MV, 10 MV and DE. For dual energy plans, all cases were optimized with identical planning objectives and normalized such 98% of the target received 100% of prescription dose.
Results: The three techniques showed comparable PTV inhomogeneity and conformity for all patient’s differences within the median values <0.6%10 MV and DE plans also additionally a statistically important reduction in the total number of monitor units (MU) of 14.2% (p <0.01) and 13.3% (p <0.01) as compared to 6 MV, respectively.
Conclusion: Each dual energy and 10 MV energy had similar PTV dosimetry characteristics.

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