• Home
  • Browse
    • Current Issue
    • By Issue
    • By Author
    • By Subject
    • Author Index
    • Keyword Index
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Editorial Staff
    • Publication Ethics
    • Indexing and Abstracting
    • Related Links
    • FAQ
    • Peer Review Process
    • News
  • Guide for Authors
  • Submit Manuscript
  • Reviewers
  • Contact Us
 
  • Login
  • Register
Home Articles List Article Information
  • Save Records
  • |
  • Printable Version
  • |
  • Recommend
  • |
  • How to cite Export to
    RIS EndNote BibTeX APA MLA Harvard Vancouver
  • |
  • Share Share
    CiteULike Mendeley Facebook Google LinkedIn Twitter
Arab Journal of Nuclear Sciences and Applications
arrow Articles in Press
arrow Current Issue
Journal Archive
Volume Volume 54 (2021)
Issue Issue 2
Issue Issue 1
Volume Volume 53 (2020)
Volume Volume 52 (2019)
Volume Volume 51 (2018)
El-Araby, E., Raafat, A., Elsonbaty, S. (2021). Radiation Synthesis of Psyllium/Frankincense Essential Oil –Based Wound Dressing Hydrogels: Antimicrobial, Antioxidant and Wound Healing Performance. Arab Journal of Nuclear Sciences and Applications, 54(2), 19-36. doi: 10.21608/ajnsa.2021.33835.1373
Eman El-Araby; Amany Raafat; Sawsan Mohammed Elsonbaty. "Radiation Synthesis of Psyllium/Frankincense Essential Oil –Based Wound Dressing Hydrogels: Antimicrobial, Antioxidant and Wound Healing Performance". Arab Journal of Nuclear Sciences and Applications, 54, 2, 2021, 19-36. doi: 10.21608/ajnsa.2021.33835.1373
El-Araby, E., Raafat, A., Elsonbaty, S. (2021). 'Radiation Synthesis of Psyllium/Frankincense Essential Oil –Based Wound Dressing Hydrogels: Antimicrobial, Antioxidant and Wound Healing Performance', Arab Journal of Nuclear Sciences and Applications, 54(2), pp. 19-36. doi: 10.21608/ajnsa.2021.33835.1373
El-Araby, E., Raafat, A., Elsonbaty, S. Radiation Synthesis of Psyllium/Frankincense Essential Oil –Based Wound Dressing Hydrogels: Antimicrobial, Antioxidant and Wound Healing Performance. Arab Journal of Nuclear Sciences and Applications, 2021; 54(2): 19-36. doi: 10.21608/ajnsa.2021.33835.1373

Radiation Synthesis of Psyllium/Frankincense Essential Oil –Based Wound Dressing Hydrogels: Antimicrobial, Antioxidant and Wound Healing Performance

Article 3, Volume 54, Issue 2, Spring 2021, Page 19-36  XML PDF (1.86 MB)
Document Type: Original Article
DOI: 10.21608/ajnsa.2021.33835.1373
Authors
Eman El-Araby email 1; Amany Raafat2; Sawsan Mohammed Elsonbaty3
1EAEA
2Chemistry Department, National Center for Radiation Research and Technology, Egyptian Atomic Energy Authority (AEAE), P.O. Box 29, Nasr City 11731, Cairo, Egypt
3Radiation microbiology, National center for radiation research and technology
Abstract
Abstract
Innovative bioactive hydrogel dressings based on Psyllium (Pys) and Carbopol (Carp) supported with Frankincense essential oil (FO) were fabricated using γ- irradiation facility for crosslinking and sterilization. (Psy-Carp)/FO dressing’s characteristics, hemolytic potential, antioxidant efficiency, antimicrobial activity as well as their morphological features were evaluated. Wound healing efficacy was evaluated using a rat model. The results revealed that the gelation degrees increased by the increase of (Psy) concentration, Carbopol content, and irradiation dose. The incorporation of FO oil up to 5% improves the swelling ability as well as the dressing porosity as shown by SEM images. The incorporation of FO oil enhances the Water Vapor Transmission Rate (WVTR), increases the antioxidant activity. Antimicrobial activity and microbial barrier potency of (Psy-Carp)/FO dressing was tested against Staphylococcus aureus (S. aureus), Escherichia coli (E. coli), and Candida albicans (C. albicans), the results showed that it attenuates microbial growth of all the tested strains after 18 h. by two log cycle and cause a high rate of microbial killing. A significant increase of protein release, decrease in Exopolysaccharides (EPS) content and decrease of membrane surface potential were noticed indicating alternation of cell membrane permeability leading to cell death. In vivo wound healing evaluation using rat model confirms that the tested dressings induce faster wound healing with improvement biochemical parameters compared with that of FO free (Psy-Carp) hydrogel. Based on the above-mentioned results, it can be concluded that (Psy-Carp)/FO hydrogel dressings demonstrate a promising potential as wound care candidates.
Keywords
Keywords:Bioactive hydrogel dressing; Frankincense Oil; Antimicrobial performance; Pathogenic microorganisms; Wound healing
Statistics
Article View: 200
PDF Download: 72
Home | Glossary | News | Aims and Scope | Sitemap
Top Top

Journal Management System. Designed by NotionWave.